Ceramic Ha Resin

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Ceramic ha resin.

Ceramic hydroxyapatite cht ceramic hydroxyapatite types i and ii are produced. Its mixed mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods. The duration and temperature of the sintering step determine whether the ceramic hydroxyapatite is cht type i or type ii. Details of the binding mechanism are described in chapter 3.

Cht is a leading purification medium of biomolecules. Hydroxyapatite is the hydroxyl endmember of the complex apatite group the oh ion can be replaced by fluoride chloride or carbonate. Cht is a mixed mode resin. Hydroxyapatite also called hydroxylapatite ha is a naturally occurring mineral form of calcium apatite with the formula ca 5 po 4 3 oh but it is usually written ca 10 po 4 6 oh 2 to denote that the crystal unit cell comprises two entities.

The ceramic material overcomes many of the limitations of traditional crystalline hydroxyapatite that prevent its use in industrial scale applications. Cht ceramic hydroxyapatite ca 5 po 4 3 oh 2 support is a leading purification medium for today s demanding downstream process industry. It has been sintered at high temperatures to modify it from a crystalline to a ceramic form. This mixed mode support offers unique selectivities and often separates biomolecules that appear homogeneous using other chromatographic methods.

Cht ceramic hydroxyapatite support is a leading purification medium for today s demanding downstream process industry.